Frequency of Hospitalized Infections Is Reduced in Rheumatoid Arthritis Patients Who Received Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs after 2010.
Kunihiro IchinoseToshimasa ShimizuMasataka UmedaShoichi FukuiAyako NishinoTomohiro KogaShin-Ya KawashiriNaoki IwamotoMami TamaiHideki NakamuraShuntaro SatoTomoki OriguchiAtsushi KawakamiPublished in: Journal of immunology research (2018)
This is the first report that the frequency of hospitalized infection significantly decreased when the patients were treated with a bDMARD or tsDMARD after 2010. Our results indicate that the updated announcement of diagnosis and treatment criteria might contribute to a reduced risk of hospitalized infection and a better understanding of the use of bDMARDs/tsDMARDs by rheumatologists.