Defining the contribution of chronic kidney disease to all-cause mortality in patients with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study.
Giuseppe PennoAnna SoliniEnzo BonoraEmanuela OrsiCecilia FondelliGianpaolo ZerbiniRoberto TrevisanMonica VedovatoFranco CavalotLuigi LaviolaAntonio NicolucciGiuseppe Pugliesenull nullPublished in: Acta diabetologica (2018)
CKD is a major contributor to excess mortality in type 2 diabetes, conferring a very high risk in younger patients and fully accounting for excess risk in the older ones. Higher albuminuria and lower eGFR, even in the normal range, identify individuals with increased mortality risk. Trial registration ClinicalTrials.gov (NCT00715481; https://clinicaltrials.gov/ct2/show/NCT00715481 ).
Keyphrases
- cardiovascular events
- chronic kidney disease
- end stage renal disease
- type diabetes
- cardiovascular disease
- coronary artery disease
- peritoneal dialysis
- small cell lung cancer
- ejection fraction
- newly diagnosed
- computed tomography
- clinical trial
- physical activity
- study protocol
- magnetic resonance
- randomized controlled trial
- phase iii
- glycemic control
- patient reported outcomes
- epidermal growth factor receptor
- metabolic syndrome
- contrast enhanced
- open label
- pet ct
- double blind