A systematic review of relapse rates during pregnancy and postpartum in patients with relapsing multiple sclerosis.
Kerstin HellwigElisabetta Verdun di CantognoMeritxell SabidóPublished in: Therapeutic advances in neurological disorders (2021)
Results of this systematic review concerning women with relapsing MS show a complex and often conflicting picture regarding DMT exposure and relapses during and after pregnancy. Although our data are limited by variability between studies, there is some evidence suggesting the use of natalizumab or fingolimod preconception is associated with increased risk of relapses during pregnancy, highlighting the need for effective disease-management strategies in these especially high-risk patients.
Keyphrases
- multiple sclerosis
- systematic review
- white matter
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- prognostic factors
- meta analyses
- peritoneal dialysis
- electronic health record
- randomized controlled trial
- ms ms
- pregnant women
- big data
- mass spectrometry
- data analysis
- artificial intelligence