Persistent β-Hexachlorocyclohexane Exposure Impacts Cellular Metabolism with a Specific Signature in Normal Human Melanocytes.
Federica PapaccioSilvia CaputoAlessandra IorioPaola De SimoneMonica OttavianiAntonella Del BroccoPasquale FrascioneBarbara BelleiPublished in: Cells (2024)
In conclusion, long-term exposure to persistent organic pollutants damages melanocyte metabolism in its function of melanin production with a consequent reduction of melanogenesis indicating a potential augmented skin cancer risk.