Cardiac remodeling and myocardial replacement fibrosis are observed frequently in the presence of substantial LV volume overload, particularly in cases with severe primary MR. CMR serves as a useful diagnostic imaging modality in assessing mitral regurgitation severity, early detection of cardiac remodeling, myocardial dysfunction, and myocardial fibrosis, enabling timely intervention before irreversible damage ensues. Incorporating myocardial remodeling in terms of left ventricular (LV) dilatation and myocardial fibrosis with quantitative MR severity assessment by CMR may assist in defining optimal timing of intervention.
Keyphrases
- left ventricular
- hypertrophic cardiomyopathy
- aortic stenosis
- acute myocardial infarction
- cardiac resynchronization therapy
- heart failure
- randomized controlled trial
- mitral valve
- left atrial
- high resolution
- oxidative stress
- magnetic resonance
- magnetic resonance imaging
- liver fibrosis
- emergency department
- computed tomography
- contrast enhanced
- photodynamic therapy
- acute coronary syndrome
- percutaneous coronary intervention
- mass spectrometry
- transcatheter aortic valve replacement