Association of Urinary Dickkopf-3 Levels with Cardiovascular Events and Kidney Disease Progression in Systolic Blood Pressure Intervention Trial.
Vanessa-Giselle PeschardRebecca ScherzerRonit KatzTeresa K ChenAlexander L BullenKasey CamposMichelle M EstrellaJoachim H IxMichael G ShlipakPublished in: Kidney360 (2024)
Among individuals with hypertension and non-diabetic CKD, higher uDKK3 appeared to have associations with a greater risk of CVD events, incident ESKD, incident AKI, eGFR decline ≥30%, and mortality, but was not independent of eGFR and albuminuria.
Keyphrases
- cardiovascular events
- blood pressure
- cardiovascular disease
- small cell lung cancer
- epidermal growth factor receptor
- tyrosine kinase
- coronary artery disease
- hypertensive patients
- heart rate
- randomized controlled trial
- type diabetes
- acute kidney injury
- study protocol
- chronic kidney disease
- clinical trial
- phase iii
- phase ii
- wound healing
- blood glucose
- heart failure
- left ventricular
- metabolic syndrome
- atrial fibrillation
- weight loss