Clinical Trials in Gastroesophageal Cancers: An Analysis of the Global Landscape of Interventional Trials From ClinicalTrials.gov.

Ayo S Falade Oluwatayo Adeoye Katherine Van Loon Geoffrey C Buckle

Published in: JCO global oncology (2024)

Although 80% of GECs occur in LMICs, trial activity disproportionately occurs in HICs. Few trials focus on EAC/ESCC despite being highly fatal, highlighting an unmet need. Overall, this study highlights (1) a missed opportunity to recruit patients from high-incidence regions globally; and (2) a pressing need for increasing funding, infrastructure, and support for GEC trials in LMICs.

Keyphrases

clinical trial
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
phase iii
study protocol
phase ii
randomized controlled trial
single cell
patient reported outcomes
double blind