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Climatic adaptation in human inferior nasal turbinate morphology: Evidence from Arctic and equatorial populations.

Tarah N MarksScott D MadduxLauren N ButaricRobert G Franciscus
Published in: American journal of physical anthropology (2019)
This study documents the existence of ecogeographic variation in human nasal turbinate morphology reflecting climate-mediated evolutionary demands on intranasal heat and moisture exchange. Humans adapted to cold-dry environments exhibit turbinate morphologies that enhance contact between respired air and nasal mucosa to facilitate respiratory air conditioning. Conversely, humans adapted to hot-humid environments exhibit turbinate morphologies that minimize air-to-mucosa contact, likely to minimize airflow resistance and/or facilitate expiratory heat-shedding.
Keyphrases
  • endothelial cells
  • climate change
  • chronic rhinosinusitis
  • induced pluripotent stem cells
  • pluripotent stem cells
  • heat stress
  • genome wide
  • dna methylation
  • mechanical ventilation
  • acute respiratory distress syndrome