The Protective Effect of Antarctic Krill Oil on Cognitive Function by Inhibiting Oxidative Stress in the Brain of Senescence-Accelerated Prone Mouse Strain 8 (SAMP8) Mice.
Qian LiFengjuan WuMin WenTeruyoshi YanagitaChanghu XueTian-Tian ZhangYuming WangPublished in: Journal of food science (2018)
The results of Morris water maze, Barnes maze test and open-field test indicated that Antarctic krill oil (AKO) improved the cognitive function and anxiety of SAMP8 mice. AKO reduced the Aβ42 level in hippocampus of SAMP8 mice. AKO ameliorated oxidative stress in brain rather than in serum and liver of SAMP8 mice.
Keyphrases
- oxidative stress
- high fat diet induced
- dna damage
- white matter
- resting state
- type diabetes
- insulin resistance
- cerebral ischemia
- signaling pathway
- wild type
- endothelial cells
- fatty acid
- functional connectivity
- adipose tissue
- diabetic rats
- depressive symptoms
- cognitive impairment
- brain injury
- induced apoptosis
- heat shock protein