Gastrointestinal dysfunction during enteral nutrition delivery in intensive care unit (ICU) patients: Risk factors, natural history, and clinical implications. A post-hoc analysis of The Augmented versus Routine approach to Giving Energy Trial (TARGET).
Tejaswini Arunachala MurthyLee-Anne S ChappleKylie M LangeChristopher K RaynerMichael HorowitzSandra L PeakeMarianne J ChapmanPublished in: The American journal of clinical nutrition (2022)
Large GRVs were more common in males and those receiving energy-dense formulae, occurred early and were short-lived, and were associated with a number of negative clinical sequelae, including increased mortality, even when adjusted for illness severity. This trial was registered at clinicaltrials.gov as NCT02306746.
Keyphrases
- intensive care unit
- risk factors
- end stage renal disease
- study protocol
- clinical trial
- phase iii
- ejection fraction
- newly diagnosed
- mechanical ventilation
- chronic kidney disease
- phase ii
- prognostic factors
- physical activity
- peritoneal dialysis
- randomized controlled trial
- cardiovascular events
- clinical practice
- patient reported outcomes