High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery.
Jeremy TurchettoAna Filipa SequeiraLaurie RamondFanny PeyssonJoana L A BrásNatalie J SaezYoan DuhooMarilyne BlémontCatarina I P D GuerreiroLoic QuintonEdwin De PauwNicolas GillesHervé DarbonCarlos M G A FontesRenaud VincentelliPublished in: Microbial cell factories (2017)
Overall this study reveals that high-throughput expression of animal venom peptides in E. coli can generate large libraries of recombinant disulphide-reticulated peptides of remarkable interest for drug discovery programs.