Multipoint pacing for cardiac resynchronisation therapy in patients with heart failure: A systematic review and meta-analysis.
Vishal Shahil MehtaMark K ElliottBaldeep Singh SidhuJustin GouldBradley PorterSteven NiedererChristopher Aldo RinaldiPublished in: Journal of cardiovascular electrophysiology (2021)
Overall MPP was more efficacious in nonrandomised studies, and not superior when assessed in randomised studies. There was considerable heterogeneity in study design making overall interpretation of results challenging. Widespread MPP programming in all CRT patients is currently not justified. Further large, randomised studies with patient-specific programming may clarify its effectiveness.
Keyphrases
- clinical trial
- end stage renal disease
- cardiac resynchronization therapy
- case control
- open label
- randomized controlled trial
- study protocol
- chronic kidney disease
- ejection fraction
- newly diagnosed
- left ventricular
- double blind
- prognostic factors
- systematic review
- peritoneal dialysis
- single cell
- placebo controlled
- stem cells
- patient reported outcomes
- mesenchymal stem cells
- bone marrow
- smoking cessation
- replacement therapy