Association of lifestyle intervention with risk for cardiovascular events differs by level of glycated hemoglobin.

Michael Patrick BancksScott J PillaAshok Balasubramanyam Hsin-Chieh YehKaren C JohnsonJoseph RigdonLynne E WagenknechtMark A Espeland

Published in: The Journal of clinical endocrinology and metabolism (2023)

Among adults with type 2 diabetes and overweight/obesity, randomization to a lifestyle intervention was differentially associated with CVD risk by baseline HbA1c such that it was associated with lower risk at lower HbA1c levels and higher risk at higher HbA1c levels. There is a critical need to develop and tailor lifestyle interventions to be successful for individuals with type 2 diabetes and high HbA1c.

Keyphrases

weight loss
cardiovascular events
physical activity
metabolic syndrome
cardiovascular disease
randomized controlled trial
coronary artery disease
adipose tissue
body mass index