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Polygene risk scores and randomized experiments.

Lauren N RossKenneth S KendlerJames F Woodward
Published in: The Behavioral and brain sciences (2023)
We explore Madole & Harden's (2022) suggestion that single-nucleotide polymorphism (SNP)/trait correlations are analogous to randomized experiments and thus can be given a causal interpretation.
Keyphrases
  • double blind
  • open label
  • placebo controlled
  • phase iii
  • genome wide
  • phase ii
  • clinical trial
  • dna methylation
  • gene expression
  • randomized controlled trial