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First-in-human phase 2 trial with mite allergoids coupled to mannan in subcutaneous and sublingual immunotherapy.

Antonio Nieto GarcíaÁngel Mazón RamosMaría NietoEthel IbáñezDah Tay JangSusana CalaforraPilar AlbaCarmen Pérez-FrancésRuth LlusarJavier MontoroAntonio de MateoRemedios AlamarDavid El-QutobFrancisco Javier Fernández SánchezLuis MoralTeresa ToralMónica AntónCarmen AndreuÁngel FerrerIsabel-María FloresNeus CerdáSandra Del PozoRaquel CaballeroJosé Luis SubizaMiguel Casanovas
Published in: Allergy (2022)
PM-HDM immunotherapy was safe and successful in achieving primary and secondary clinical outcomes in SC and SL at either 3000 or 5000 mTU/ml.
Keyphrases
  • endothelial cells
  • allergic rhinitis
  • particulate matter
  • air pollution
  • induced pluripotent stem cells
  • heavy metals
  • pluripotent stem cells
  • polycyclic aromatic hydrocarbons
  • risk assessment
  • water soluble