Comparison of intestinal expression of the apical sodium-dependent bile acid transporter between dogs with and without chronic inflammatory enteropathy.
Paula Roberta GiarettaRaquel R RechBlake C GuardAmanda B BlakeAnna K BlickJoerg M SteinerJonathan A LidburyAudrey K CookMohsen HanifehThomas SpillmannSusanne KilpinenPernilla SyrjäJan S SuchodolskiPublished in: Journal of veterinary internal medicine (2018)
These findings indicate that ileal protein expression of ASBT is downregulated in dogs with CIE. This change may be linked to the inflammatory process, intestinal dysbiosis, and fecal bile acid dysmetabolism observed in these patients.