Efficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials.

Nicolas A Nunez Balwinder SinghFrancisco Romo-NavaBoney JosephMarin VeldicAlfredo B Cuellar BarbozaAlejandra Cabello ArreolaJennifer L Vande VoortPaul CroarkinKatherine M MooreJoanna M BiernackaSusan L McElroyMark A Frye

Published in: Bipolar disorders (2020)

This narrower scope meta-analysis of one drug for one disease suggests that adjunctive MoArm may represent a novel therapeutic intervention. Further studies delineating the subtypes of bipolar depression responsive to these novel dopaminergic-enhancing agents are encouraged.

Keyphrases

depressive symptoms
bipolar disorder
sleep quality
randomized controlled trial
systematic review
open label
drug delivery
drug induced
electronic health record