Higher Levels of C-reactive Protein are Associated with Higher Cortical Surface Area and Lower Cortical Thickness in Youth with Bipolar Disorder.
Suyi ShaoYi ZouKody G KennedyMikaela K DimickBradley J MacIntoshBenjamin I GoldsteinPublished in: The international journal of neuropsychopharmacology (2023)
This study found that higher CRP among youth with BD is associated with higher SA but lower cortical thickness in ROI and vertex-wise analyses. The study identified two regions in which the association of CRP with brain structure differs between youth with BD vs. CG. Future longitudinal, repeated-measures studies incorporating additional inflammatory markers are warranted.