MAPT expression is mediated by long-range interactions with cis -regulatory elements.

Brianne B RogersAshlyn G AndersonShelby N LauzonM Natalie DavisRebecca M HauserSydney C RobertsIvan Rodriguez-NunezKatie Trausch-LowtherErin A BarinagaJared W TaylorMark MackiewiczBrian S RobertsSara J CooperLindsay F RizzardiRichard M MyersJesse Nicholas Cochran

Published in: bioRxiv : the preprint server for biology (2023)

beyond the well-described H1/H2 haplotype inversion breakpoint. This study provides compelling evidence for pursuing detailed knowledge of CREs for genes of interest to permit better understanding of disease risk.

Keyphrases

poor prognosis
healthcare
genome wide
transcription factor
gene expression
bioinformatics analysis
computed tomography
genome wide identification
magnetic resonance imaging