Comprehensive exploratory autoantibody profiling in patients with early rheumatoid arthritis treated with methotrexate or tocilizumab.
Xavier M TeitsmaJenny DevenportJohannes W G JacobsAttila Pethö-SchrammMichelle E A BormPetra BuddeJohannes W J BijlsmaFloris P J G LafeberPublished in: PloS one (2020)
Comprehensive profiling of baseline sera revealed several novel immunoglobin G autoantibodies associated with early treatment response to methotrexate and to tocilizumab in disease-modifying anti-rheumatic drug-naive patients with rheumatoid arthritis. These findings could eventually yield clinically relevant predictive markers, if corroborated in different patient cohorts, and may facilitate future benefit in personalised healthcare.