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Lysophosphatidic acid (LPA)-antibody (504B3) engagement detected by interferometry identifies off-target binding.

Manisha RayYasuyuki KiharaDarryl J BornhopJerold Chun
Published in: Lipids in health and disease (2021)
Antibody binding specificity and sensitivity, particularly involving lipid ligands, can be assessed in solution and without labels using FSA-CIR. These findings could affect interpretations of both current and past basic and clinical studies employing 504B3 and related anti-LPA antibodies.
Keyphrases
  • dna binding
  • genome wide
  • social media
  • binding protein
  • high speed
  • gene expression
  • fatty acid
  • dna methylation