In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.

Caterina IeranòDario RighelliCrescenzo D'AlterioMaria NapolitanoLuigi PortellaGiuseppina ReaFederica AulettaSara SantagataAnna Maria TrottaGiuseppe GuardascioneFederica LiottiNella PrevetePiera MaiolinoAntonio LucianoAntonio BarbieriAnnabella Di MauroCristin RomaRiziero Esposito AbateFabiana TatangeloRoberto PacelliNicola NormannoRosa Marina MelilloStefania Scala

Published in: Journal for immunotherapy of cancer (2022)

In PD-1+ human colon cancer cells, NIVO activates tumor survival pathways and could protect tumor cells from conventional therapies.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells