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Accelerated Barrier Repair in Human Skin Explants Induced with a Plant-Derived PPAR-α Activating Complex via Cooperative Interactions.

George P MajewskiJohn CrawTimothy Falla
Published in: Clinical, cosmetic and investigational dermatology (2021)
These findings suggest that the RFV3 complex successfully mimics a PPAR-α agonist and induces synthesis of skin barrier lipids and proteins consistent with known PPAR pathways.
Keyphrases
  • insulin resistance
  • fatty acid
  • signaling pathway
  • high glucose
  • diabetic rats
  • drug induced
  • adipose tissue
  • soft tissue
  • skeletal muscle
  • wound healing
  • oxidative stress
  • cell wall