Effects of a Single Oral Megadose of Vitamin D3 on Inflammation and Oxidative Stress Markers in Overweight and Obese Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Laine de Carvalho Guerra Pessoa MamedeRafaela Lira Formiga Cavalcanti de LimaAlexandre Sérgio SilvaJoão Carlos Lima Rodrigues PitaNadjeanny Ingrid Galdino GomesElisama Araújo de SenaRhayra Priscila Moraes NobregaJoão Otávio Scarano AlcântaraJulie Hanna Fontes de SouzaGlêbia Alexa CardosoJosé Luiz de Brito AlvesMaria da Conceição Rodrigues GonçalvesPublished in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)
In summary, a single oral megadose of VD3 increased 25-hydroxyvitamin D serum levels but did not improve oxidative stress and inflammation markers.
Keyphrases
- oxidative stress
- double blind
- placebo controlled
- clinical trial
- phase ii
- diabetic rats
- phase iii
- study protocol
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- polycystic ovary syndrome
- randomized controlled trial
- open label
- metabolic syndrome
- pregnancy outcomes
- insulin resistance
- adipose tissue
- heat shock
- breast cancer risk
- signaling pathway
- squamous cell carcinoma
- type diabetes
- rectal cancer