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Characterisation of gut microbiota composition in patients with axial spondyloarthritis and its modulation by TNF inhibitor treatment.

Marie VallierBéatrice SegurensElise LarsonneurVincent MeyerStephanie FerreiraChristophe CaloustianJean-François DeleuzeMaxime DougadosMathias ChamaillardCorinne Miceli-Richard
Published in: RMD open (2023)
Several SpA patients' characteristics modulate the composition of gut microbiota as did TNFi treatment. Moreover, the abundance/prevalence of seven OTUs at baseline may be used as a novel non-invasive index that predicts the response to TNFi with greater accuracy than HLA-B27 status, CRP level and measures of disease activity.
Keyphrases
  • disease activity
  • rheumatoid arthritis
  • systemic lupus erythematosus
  • ankylosing spondylitis
  • rheumatoid arthritis patients
  • newly diagnosed
  • ejection fraction
  • combination therapy
  • juvenile idiopathic arthritis