Characterisation of gut microbiota composition in patients with axial spondyloarthritis and its modulation by TNF inhibitor treatment.
Marie VallierBéatrice SegurensElise LarsonneurVincent MeyerStephanie FerreiraChristophe CaloustianJean-François DeleuzeMaxime DougadosMathias ChamaillardCorinne Miceli-RichardPublished in: RMD open (2023)
Several SpA patients' characteristics modulate the composition of gut microbiota as did TNFi treatment. Moreover, the abundance/prevalence of seven OTUs at baseline may be used as a novel non-invasive index that predicts the response to TNFi with greater accuracy than HLA-B27 status, CRP level and measures of disease activity.