Performance evaluation of a prototype rapid diagnostic test for combined detection of gambiense human African trypanosomiasis and malaria.

Crispin LumbalaEnock MatovuHakim SendagireAnne J N KazibweJoris L LikwelaHypolite Muhindo MavokoSimon KayembePascal LutumbaSylvain BiélerJean-Pierre Van GeertruydenJoseph Mathu Ndung'u

Published in: PLoS neglected tropical diseases (2020)

The HAT/Malaria Combined prototype RDT was as accurate as the individual malaria or gHAT RDTs. The HAT/Malaria Combined prototype RDT is therefore suitable for both malaria diagnosis and gHAT screening. However, there is a need to assess its accuracy using fresh samples in prospective clinical trials.

Keyphrases

plasmodium falciparum
clinical trial
endothelial cells
loop mediated isothermal amplification
randomized controlled trial
high resolution
mass spectrometry
sensitive detection