Low BCL9 expression inhibited ovarian epithelial malignant tumor progression by decreasing proliferation, migration, and increasing apoptosis to cancer cells.
Jing WangMingjun ZhengLiancheng ZhuLu DengXiao LiLinging GaoCaixia WangHuimin WangJuanjuan LiuBei LinPublished in: Cancer cell international (2019)
BCL9 is overexpressed in epithelial ovarian tumors, resulting in a poor prognosis for ovarian cancer patients. Low BCL9 expression can promote ovarian cancer cell apoptosis, inhibit proliferation and migration. BCL9 promotes the development of ovarian cancer.