Impact of a preceding radiotherapy on the outcome of immune checkpoint inhibition in metastatic melanoma: a multicenter retrospective cohort study of the DeCOG.
Sarah KnispelAndreas StangLisa ZimmerHildegard LaxRalf GutzmerLucie HeinzerlingCarsten WeishauptClaudia PföhlerAnja GesierichRudolf HerbstKatharina C KaehlerBenjamin WeideCarola BerkingCarmen LoquaiJochen UtikalPatrick TerheydenMartin KaatzMax SchlaakAlexander KreuterJens UlrichPeter MohrEdgar DippelElisabeth LivingstoneJürgen Christian BeckerMichael WeichenthalEleftheria ChortiJanine GronewoldDirk SchadendorfSelma UgurelPublished in: Journal for immunotherapy of cancer (2021)
This study detected no evidence for a relevant favorable impact of a preceding radiotherapy on anti-CTLA-4 or anti-PD-1 ICI treatment outcome in metastatic melanoma.