Home-based management of hypoxaemic COVID-19 patients: design of the Therapy@Home pilot study.
Josi A BoeijenAlma C van de PolRick T van UumRoderick P VenekampKarin SmitKarin A H KaasjagerRobert van den BroekWilma BijsterboschLisette SchoonhovenFrans H RuttenDorien L M ZwartPublished in: BMJ open (2024)
All patients will provide written, informed consent. The study was approved by the Medical Ethics Review Committee of the University Medical Center Utrecht, the Netherlands (protocol NL77421.041.21). The preparatory steps (1-4) needed to perform the pilot are executed and described in this paper. The findings of the pilot will be published in academic journals. If we consider the complex intervention feasible, we aim to continue with a large-scale randomised controlled study evaluating the clinical effectiveness, safety and implementation of the complex intervention.
Keyphrases
- randomized controlled trial
- study protocol
- healthcare
- end stage renal disease
- clinical trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- sars cov
- primary care
- public health
- systematic review
- open label
- peritoneal dialysis
- stem cells
- prognostic factors
- intensive care unit
- machine learning
- mesenchymal stem cells
- big data
- quality improvement
- artificial intelligence