Clinical Outcomes With Definitive Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia With Retained Daptomycin and Ceftaroline Combination Therapy vs De-escalation to Monotherapy With Vancomycin, Daptomycin, or Ceftaroline.
Courtney N NicholsLynn C WardlowKelci E CoeMohammad Mahdee E SobhaniePublished in: Open forum infectious diseases (2021)
No difference was found in the composite outcome of 60-day bacteremia recurrence, readmission, or inpatient infection-related mortality for patients with MRSA bacteremia retained on combination therapy versus those de-escalated to monotherapy.
Keyphrases
- combination therapy
- methicillin resistant staphylococcus aureus
- staphylococcus aureus
- gram negative
- mental health
- palliative care
- cardiovascular events
- multidrug resistant
- risk factors
- squamous cell carcinoma
- randomized controlled trial
- cardiovascular disease
- free survival
- type diabetes
- locally advanced
- study protocol
- drug induced