Polyunsaturated fatty acids alter the formation of lipid droplets and eicosanoid production in Leishmania promastigotes.

Yasmin Monara Ferreira de Sousa AndradeMonara Viera de CastroVictor de Souza TavaresRayane da Silva Oliveira SouzaLúcia Helena FaccioliJonilson Berlink LimaCarlos Arterio SorgiValéria M BorgesThéo Araujo-Santos

Published in: Memorias do Instituto Oswaldo Cruz (2023)

Our data suggest LD formation and eicosanoid production are distinctly modulated by PUFAS dependent of Leishmania species. In addition, eicosanoid-enzyme mutations are more similar between Leishmania species with same host tropism.

Keyphrases

electronic health record
genetic diversity
fatty acid
machine learning
data analysis