Cardiac structural and functional abnormalities in epilepsy: A systematic review and meta-analysis.
Zining LiuPeravina ThergarajanAna Antonic-BakerZhibin Chen MBiostatPaul B SparksNatasha A LanninPatrick KwanNigel Charles JonesPablo Miguel Casillas-EspinosaPiero PeruccaTerence J O'BrienShobi SivathambooPublished in: Epilepsia open (2023)
Our findings suggest that epilepsy is associated with altered diastolic and systolic echocardiogram parameters compared with healthy controls. Notably, SUDEP does not appear to be associated with a higher incidence of structural cardiac abnormalities, compared with non-SUDEP epilepsy controls. Longitudinal studies are needed to understand the prognostic significance of such changes. Echocardiography may be a useful noninvasive diagnostic test in epilepsy population.