Placental expression of lysophosphatidic acid receptors in normal pregnancy and preeclampsia.

Tatsuya Fujii Takeshi NagamatsuDanny J SchustMayuko IchikawaKeiichi KumasawaShinichiro YabeTakayuki IriyamaYasushi HirotaYutaka OsugaJunken AokiYutaka YatomiTomoyuki Fujii

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2019)

In summary, the placental expression of LPARs, particularly LPAR3, is enhanced in preeclampsia, suggesting that disturbances in placental LPA signaling may be involved in the pathogenesis of preeclampsia.

Keyphrases

early onset
poor prognosis
pregnancy outcomes
pregnant women
preterm birth