Sex differences in lower urinary tract function in mice with or without spinal cord injury.

Mamoru HashimotoSergei KarnupStephanie L DaughertyKang Jun ChoEri BannoNobutaka ShimizuKazutoshi FujitaAkihide HirayamaHirotsugu UemuraWilliam C de GroatJonathan M Beckel Naoki Yoshimura

Published in: Neurourology and urodynamics (2023)

We demonstrated that female and male mice voided during EUS relaxation and EUS bursting activity, respectively. Also, upregulation of TRPV1 and Piezo2 in L6-S1 DRG and NGF in the bladder could be involved in SCI-induced lower urinary tract dysfunction in both sexes of mice.

Keyphrases

urinary tract
spinal cord injury
high fat diet induced
neuropathic pain
spinal cord
fine needle aspiration
diabetic rats
oxidative stress
poor prognosis
signaling pathway
growth factor
single molecule
insulin resistance
wild type
skeletal muscle