Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration.

Samuel D JohnsonNageswara PilliJianshi YuLindsey A KnightMaureen A Kane Siddappa N Byrareddy

Published in: Annals of medicine (2024)

Taken together, these data demonstrate the therapeutic advantages of anti-α4β7 antibody administration during HIV/SIV infection and that the efficacy of anti-α4β7 antibody may depend on microbiome composition and SCFA generation.

Keyphrases

fatty acid
antiretroviral therapy
hiv positive
microbial community
human immunodeficiency virus
hiv testing
hiv aids
electronic health record
machine learning
men who have sex with men
south africa