Phase I dose-escalation oncology trials with sequential multiple schedules.
Burak Kürsad GünhanSebastian WeberAbdelkader SeroutouTim FriedePublished in: BMC medical research methodology (2021)
In phase I oncology trials with sequential multiple schedules, the use of all relevant information is of great importance. For these trials, the adapted TITE-PK which combines information using PK principles is recommended.