Expression of SASH1 in Preeclampsia and Its Effects on Human Trophoblast.

Shisan LiuSijia JiangLiping Huang Yanhong Yu

Published in: BioMed research international (2020)

SASH1 is significantly upregulated in the placenta of preeclampsia, and overexpression of SASH1 can inhibit the proliferation, migration, and invasion, but induce apoptosis of trophoblast cells in vitro.

Keyphrases

cell cycle arrest
induced apoptosis
early onset
cell death
endoplasmic reticulum stress
endothelial cells
pi k akt
poor prognosis
signaling pathway
oxidative stress
cell proliferation
pregnancy outcomes
induced pluripotent stem cells
transcription factor
pregnant women
long non coding rna