Impact of angiogenesis inhibitor eligibility on the prognosis of patients with non-small cell lung cancer harboring EGFR mutation.
Hiroaki KodamaHirotsugu KenmotsuTakanori KawabataAkifumi NotsuMichitoshi YabeNaoya NishiokaEriko MiyawakiTaichi MiyawakiNobuaki MamesayaHaruki KobayashiShota OmoriKazushige WakudaAkira OnoTateaki NaitoHaruyasu MurakamiToshiaki TakahashiPublished in: Cancer medicine (2021)
From our study, AI eligibility resulted in longer OS and PFS, and also had different effects on patients with EGFR L858R and exon 19 deletion. Since this selection bias may have affected previous clinical trial data on the efficacy of AI combination therapy, their results should be carefully considered henceforth.