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Earliest observation of the tetracycline destructase tet(X3 ).

Frédéric GrenierSimon LévesqueSébastien RodrigueLouis-Patrick Haraoui
Published in: Microbiology spectrum (2024)
)-positive strain we report is the first and only to be found that predates the commercialization of tigecycline, an antibiotic that was thought to have contributed to the emergence of this resistance gene. Understanding the factors contributing to the origin and spread of novel antibiotic resistance genes is crucial to addressing the major global public health issue, which is antimicrobial resistance.
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