Intraindividual Neurofilament Dynamics in Serum Mark the Conversion to Sporadic Parkinson's Disease.
Carlo WilkeMarcia Cristina Teixeira Dos SantosClaudia SchulteChristian DeuschleDieter SchellerMoira VerbelenKathrin BrockmannAnna-Katharina von ThalerUlrike SünkelBenjamin RoebenSarah BujacFlorian G MetzgerWalter MaetzlerAndre Nogueira da CostaMatthis SynofzikDaniela BergPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
The temporal dynamics of intraindividual NfL blood levels might mark the conversion to clinically manifest PD, providing a potential stratification biomarker for individual disease onset in the advent of precision medicine for PD. © 2020 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.