Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study.
Patrick TrépanierDiane FournierCarl SimardMagali J FontaineDavid StroncekMinoko TakanashiDavid McKennaJoseph SchwartzYvette C TanhehcoJo-Anna ReemsSilvia TorrentsGesine KoglerStefanie LiedtkeMartin GirouxJelena L HolovatiIsabelle LouisArun PrasathNicolas PineaultRenée Bazinnull nullPublished in: Transfusion (2022)
Excellent qualitative and quantitative agreement was exhibited across laboratories. The IL-3-pSTAT5 assay may therefore be implemented in flow cytometry laboratories to rapidly and reliably provide standardized measures of stem cell potency in CBUs.