Systematic review with network meta-analysis: comparative efficacy of pharmacologic therapies for fibrosis improvement and resolution of NASH.

Abdul M MajzoubTarek NayfehAbbey BarnardNagambika MunaganuruShravan DaveSiddharth SinghMohammad Hassan MuradStephen Caldwell

Published in: Alimentary pharmacology & therapeutics (2021)

These data provide relative rank-order efficacy of various NASH therapies in terms of their improvements in liver fibrosis and NASH resolution. Therapies that have been shown to improve NASH resolution may be combined with therapies that have an antifibrotic effect to further boost treatment response rate in future.

Keyphrases

systematic review
liver fibrosis
meta analyses
single molecule
randomized controlled trial
electronic health record
current status
big data
data analysis