Fasting hyperglycaemia and fatty liver drive colorectal cancer: a retrospective analysis in 1145 patients.

Lucilla CrudeleCarlo De MatteisFabio NovielliStefano PetruzzelliErsilia Di BuduoGiusi GrazianoMarica CarielloElena PiccininRaffaella Maria GadaletaAntonio Moschetta

Published in: Internal and emergency medicine (2024)

MASLD and increased FPG may play a role in the clinical background of CRC, bringing to light the fascinating possibility of a reversed gut-liver axis communication in the pathogenesis of CRC. Thus, the use of non-invasive scores of fatty liver may be helpful to predict the risk of CRC and serve as novel prognostic factors for prevention and therapeutic strategies.

Keyphrases

prognostic factors
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
peritoneal dialysis
fatty acid
skeletal muscle
blood glucose
weight loss