Modeling miRNA-mRNA interactions that cause phenotypic abnormality in breast cancer patients.

Published in: PloS one (2017)

The MBS algorithm successfully learned miRNA and mRNA expression profile data using a BN, and identified miRNA-mRNA interactions that probabilistically affect breast cancer pathogenesis. The MBS algorithm is a potentially useful tool for identifying interacting gene pairs implicated by the deregulation of expression.

Keyphrases

binding protein
machine learning
deep learning
poor prognosis
copy number
artificial intelligence
dna methylation
long non coding rna