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On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors.

Simon Bendt ChristensenAnna Mette HansenHenrik Franzyk
Published in: Journal of peptide science : an official publication of the European Peptide Society (2017)
4-Nitrophenyl formate was found to be the most convenient reagent in solid-phase formylation of peptides with a high formylation degree within 20 min to 3 h depending on reaction temperature and length of peptide.
Keyphrases
  • optic nerve
  • amino acid