Henrik Franzyk

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

Journal of medicinal chemistry

International journal of molecular sciences

Molecules (Basel, Switzerland)

Amino acids

University of Copenhagen

Technical University of Denmark (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Sep 15 2000

Denmark

Associate professor :: Department of Drug Design and Pharmacology

Technical University of Denmark Jan 01 1998 - Aug 31 2000

Denmark

Research associate professor :: Dept. Organic Chemistry

Technical University of Denmark Jul 01 1997 - Dec 31 1997

Denmark

Research assistant professor :: Dept. Organic Chemistry

Carlsberg Laboratory Apr 01 1994 - Jul 01 1996

Denmark

Postdoc

Education History

Technical University of Denmark Feb 01 1991 - Nov 04 1993

Denmark

PHD :: Dept. Organic Chemistry

Publications

Johan Storm Jørgensen, Elnaz Harifi Mood, Anne Sofie Holst Knap, Simone Eidnes Nielsen, Peter E Nielsen, Dorota Żabicka, Carina Matias, Ilona Domraceva, Fredrik Björkling, Henrik Franzyk
Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids. Journal of medicinal chemistry 67 (2) (2024)
Johan Storm Jørgensen, Elnaz Harifi Mood, Anne Sofie Holst Knap, Simone Eidnes Nielsen, Peter E Nielsen, Dorota Żabicka, Carina Matias, Ilona Domraceva, Fredrik Björkling, Henrik Franzyk
Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids. Journal of medicinal chemistry 67 (2) (2024)
Johan Storm Jørgensen, Elnaz Harifi Mood, Anne Sofie Holst Knap, Simone Eidnes Nielsen, Peter E Nielsen, Dorota Żabicka, Carina Matias, Ilona Domraceva, Fredrik Björkling, Henrik Franzyk
Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids. Journal of medicinal chemistry (2024)
Johan Storm Jørgensen, Elnaz Harifi Mood, Anne Sofie Holst Knap, Simone Eidnes Nielsen, Peter E Nielsen, Dorota Żabicka, Carina Matias, Ilona Domraceva, Fredrik Björkling, Henrik Franzyk
Polymyxins with Potent Antibacterial Activity against Colistin-Resistant Pathogens: Fine-Tuning Hydrophobicity with Unnatural Amino Acids. Journal of medicinal chemistry 67 (2) (2024)
Ingvill Pedersen Sæbø, Magnar Bjørås, Henrik Franzyk, Emily Helgesen, James Alexander Booth
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity. International journal of molecular sciences 24 (3) (2023)
Ditlev Birch, Edward John Sayers, Malene V Christensen, Arwyn Tomos Jones, Henrik Franzyk, Hanne Mørck Nielsen
Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin. Pharmaceutics 15 (6) (2023)
Ingvill Pedersen Sæbø, Magnar Bjørås, Henrik Franzyk, Emily Helgesen, James Alexander Booth
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity. International journal of molecular sciences 24 (3) (2023)
Aiva Plotniece, Arkadij Sobolev, Claudiu T Supuran, Fabrizio Carta, Fredrik Björkling, Henrik Franzyk, Jari T Yli-Kauhaluoma, Koen Augustyns, Paul Cos, Linda De Vooght, Matthias Govaerts, Juliana Aizawa, Päivi Tammela, Raivis Žalubovskis
Selected strategies to fight pathogenic bacteria. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Ditlev Birch, Edward John Sayers, Malene V Christensen, Arwyn Tomos Jones, Henrik Franzyk, Hanne Mørck Nielsen
Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin. Pharmaceutics 15 (6) (2023)
Ingvill Pedersen Sæbø, Magnar Bjørås, Henrik Franzyk, Emily Helgesen, James Alexander Booth
Optimization of the Hemolysis Assay for the Assessment of Cytotoxicity. International journal of molecular sciences 24 (3) (2023)
Aiva Plotniece, Arkadij Sobolev, Claudiu T Supuran, Fabrizio Carta, Fredrik Björkling, Henrik Franzyk, Jari T Yli-Kauhaluoma, Koen Augustyns, Paul Cos, Linda De Vooght, Matthias Govaerts, Juliana Aizawa, Päivi Tammela, Raivis Žalubovskis
Selected strategies to fight pathogenic bacteria. Journal of enzyme inhibition and medicinal chemistry 38 (1) (2023)
Moa Viklund, Johanna Fredriksson, André Holdfeldt, Simon Lind, Henrik Franzyk, Claes Dahlgren, Martina Sundqvist, Huamei Forsman
Structural Determinants in the Staphylococcus aureus -Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation. Journal of immunology (Baltimore, Md. : 1950) 208 (7) (2022)
Yibing Ma, Mattia Pirolo, Prabha Subramani, Ronette Gehring, Peter Damborg, Henrik Franzyk, Luca Guardabassi
Macrolide Resistance and <i>In Vitro</i> Potentiation by Peptidomimetics in Porcine Clinical Escherichia coli. mSphere 7 (5) (2022)
Ida Kristine Lysgaard Andersen, Thomas T Thomsen, Jasmina Rashid, Thomas Rønnemoes Bobak, Alberto Oddo, Henrik Franzyk, Anders Løbner-Olesen, Paul Robert Hansen
C -Locked Analogs of the Antimicrobial Peptide BP214. Antibiotics (Basel, Switzerland) 11 (8) (2022)
Nicki Frederiksen, Stavroula Louka, Chirag Mudaliar, Ilona Domraceva, Agrita Kreicberga, Osvalds Pugovics, Dorota Żabicka, Magdalena Tomczak, Weronika Wygoda, Fredrik Björkling, Henrik Franzyk
Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties. International journal of molecular sciences 22 (13) (2021)
Victoria L Luck, David P Richards, Ashif Y Shaikh, Henrik Franzyk, Ian R Mellor
The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria. Molecules (Basel, Switzerland) 26 (22) (2021)
Henrik Franzyk, Søren Brøgger Christensen
Targeting Toxins toward Tumors. Molecules (Basel, Switzerland) 26 (5) (2021)
Anita Wester, Fredrik Björkling, Henrik Franzyk
Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation. The Journal of organic chemistry 86 (21) (2021)
Malene J Petersen, Xamuel L Lund, Susan J Semple, Bevan J Buirchell, Henrik Franzyk, Michael Gajhede, Kenneth Thermann Kongstad, Jan Stenvang, Dan Staerk
Reversal of ABCG2/BCRP-Mediated Multidrug Resistance by 5,3',5'-Trihydroxy-3,6,7,4'-Tetramethoxyflavone Isolated from the Australian Desert Plant Eremophila galeata Chinnock. Biomolecules 11 (10) (2021)
Martin Vestergaard, Bolette Skive, Ilona Domraceva, Hanne Ingmer, Henrik Franzyk
Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci: Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties. International journal of molecular sciences 22 (11) (2021)
Elnaz Harifi Mood, Lise Goltermann, Camilla Brolin, Lina M Cavaco, Alireza Japoni Nejad, Niloofar Yavari, Nicki Frederiksen, Henrik Franzyk, Peter E Nielsen
Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic. ACS infectious diseases 7 (8) (2021)
Maria Rosa Loffredo, Filippo Savini, Sara Bobone, Bruno Casciaro, Henrik Franzyk, Maria Luisa Mangoni, Lorenzo Stella
Inoculum effect of antimicrobial peptides. Proceedings of the National Academy of Sciences of the United States of America 118 (21) (2021)
Anita Wester, Anna Mette Hansen, Paul Robert Hansen, Henrik Franzyk
Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods. Amino acids 53 (9) (2021)
Nicki Frederiksen, Paul Robert Hansen, Dorota Żabicka, Magdalena Tomczak, Malgorzata Urbas, Ilona Domraceva, Fredrik Björkling, Henrik Franzyk
Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity. ChemMedChem 15 (24) (2020)
Signe Kaustrup Jensen, Thomas T Thomsen, Alberto Oddo, Henrik Franzyk, Anders Løbner-Olesen, Paul Robert Hansen
Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position. International journal of molecular sciences 21 (16) (2020)
Nicki Frederiksen, Paul Robert Hansen, Fredrik Björkling, Henrik Franzyk
Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity. Molecules (Basel, Switzerland) 24 (24) (2019)
Malene V Christensen, Kenneth Thermann Kongstad, Teis Esben Søndergaard, Dan Staerk, Hanne Mørck Nielsen, Henrik Franzyk, Reinhard Wimmer
19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR. Journal of biomolecular NMR 73 (3-4) (2019)
Hamid S Kachel, Henrik Franzyk, Ian R Mellor
Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency. Journal of medicinal chemistry 62 (13) (2019)
Rita de Cássia Lemos Lima, Kenneth Thermann Kongstad, Lucília Kato, Marcos José das Silva, Henrik Franzyk, Dan Staerk
High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules (Basel, Switzerland) 23 (7) (2018)
Natalia Molchanova, Paul Robert Hansen, Peter Damborg, Henrik Franzyk
Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius. Journal of peptide science : an official publication of the European Peptide Society 24 (7) (2018)
Anna Mette Hansen, Sarah Line Skovbakke, Simon Bendt Christensen, Iris Perez-Gassol, Henrik Franzyk
Studies on acid stability and solid-phase block synthesis of peptide-peptoid hybrids: ligands for formyl peptide receptors. Amino acids 51 (2) (2018)
Tomas Zimmermann, Søren Brøgger Christensen, Henrik Franzyk
Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis. Molecules (Basel, Switzerland) 23 (6) (2018)
Tomas Zimmermann, Henrik Franzyk, Søren Brøgger Christensen
Phorbol Rearrangements. Journal of natural products 81 (9) (2018)
Sarah Line Skovbakke, André Holdfeldt, Christina Nielsen, Anna Mette Hansen, Iris Perez-Gassol, Claes Dahlgren, Huamei Forsman, Henrik Franzyk
Combining Elements from Two Antagonists of Formyl Peptide Receptor 2 Generates More Potent Peptidomimetic Antagonists. Journal of medicinal chemistry 60 (16) (2017)
Simon Bendt Christensen, Anna Mette Hansen, Henrik Franzyk
On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors. Journal of peptide science : an official publication of the European Peptide Society 23 (5) (2017)
Rie S Kallerup, Henrik Franzyk, Mikkel L Schiøth, Sarah Justesen, Birte Martin-Bertelsen, Fabrice Rose, Cecilie M Madsen, Dennis Christensen, Karen S Korsholm, Anan Yaghmur, Camilla Foged
Adjuvants Based on Synthetic Mycobacterial Cord Factor Analogues: Biophysical Properties of Neat Glycolipids and Nanoself-Assemblies with DDA. Molecular pharmaceutics 14 (7) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Henrik Franzyk