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Early atypical signs and insula hypometabolism predict survival in multiple system atrophy.

Stéphane GrimaldiMohamed BoucekineTatiana WitjasFrederique FluchereJean-Philippe AzulayEric GuedjAlexandre Eusebio
Published in: Journal of neurology, neurosurgery, and psychiatry (2021)
The clinical prognosis factors we have described support published studies. Here, we also suggest that brain PET is of interest for prognosis assessment and in particular in the search for left insula hypometabolism. Moreover, SSRIs are a potential drug candidate to slow the progression of the disease.
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