Therapeutic targeting at genome mutations of liver cancer by the insertion of HSV1 thymidine kinase through Cas9-mediated editing.
Muhamuda KaderWei SunBao-Guo RenYan-Ping YuJunyan TaoLesley M FoleySilvia LiuSatdarshan P MongaJian-Hua LuoPublished in: Hepatology communications (2024)
Our studies suggested that mutation targeting may hold promise as a versatile and effective approach to treating liver cancers.