Hydrophilic/Hydrophobic Janus Nanofibers Containing Compound K for Cartilage Regeneration.

Hyun Ho ShinJunyoung ParkYeo-Jin KimDonghyeon KimEun-Jung Jin Ji Hyun Ryu

Published in: International journal of nanomedicine (2024)

CHI-GA/CK/PCL NFs were effective in the treatments of cartilage defects by inhibiting the expression levels of genes involved in cartilage degradation, inflammation, and lipogenesis as well as reducing lipid accumulation and the expression level of IL-1β via increasing PPAR.

Keyphrases

poor prognosis
extracellular matrix
stem cells
oxidative stress
pet ct
binding protein
signaling pathway
liquid chromatography
mass spectrometry
metabolic syndrome
protein kinase
wound healing