SARS-CoV-2 Infection during Delivery Causes Histopathological Changes in the Placenta.
Jędrzej BorowczakAgnieszka Gąsiorek-KwiatkowskaKrzysztof SzczerbowskiMateusz ManiewskiMarek ZdrenkaMarta Szadurska-NogaKarol GostomczykPaula RutkiewiczKatarzyna OlejnikWojciech CnotaMagdalena Karpów-GreinerWojciech KnypińskiMarta Sekielska-DomanowskaGrzegorz LudwikowskiMariusz DubielŁukasz SzylbergMagdalena BodnarPublished in: Diseases (Basel, Switzerland) (2024)
SARS-CoV-2 is associated with pathological changes in the placenta, including trophoblast necrosis, calcification, and accelerated villous maturation. Those changes appear to be driven by T cells and macrophages, whose increased expression reflects ongoing histiocytic intervillositis in the placenta.